Federal law enforcement has opened a formal investigation into the death of Jim Irsay, the longtime owner of the Indianapolis Colts who died in May 2025. The inquiry, led by the FBI, is focused on Irsay’s use of prescription medications and ketamine in the months leading up to his death, as well as his connection with a California-based addiction specialist. Officials have issued grand jury subpoenas seeking records related to these matters.
🔍 FBI Focuses on Substance Use and Treatment Connections
Federal investigators are scrutinizing the circumstances surrounding Irsay’s death, particularly his reported use of both prescription drugs and ketamine. The probe is also examining his relationship with Dr. Harry Haroutunian, an addiction specialist from California who treated Irsay in his final months. Authorities have issued subpoenas through a federal grand jury to obtain medical and communications records tied to the case.
While the Colts organization has acknowledged awareness of the federal inquiry, team officials say they have not received any subpoenas nor been directly contacted by the FBI.
📅 Background: Irsay’s Passing and Treatment History
Jim Irsay, 65, died at the Beverly Hills Hotel in California in May 2025. His death certificate, signed by his treating physician, listed cardiac arrest due to pneumonia and heart complications as the cause of death, though no autopsy was performed.
Reports indicate that in the months before his death, Irsay had been prescribed a large number of opioid pain medications and had received ketamine treatments, raising concerns among those close to him about a possible relapse into substance abuse. Previous incidents included multiple suspected overdoses in late 2023, though the details were not widely publicized at the time.
🏈 Legacy and Ongoing Impact
Irsay was one of the most prominent figures in the National Football League, owning the Colts since 1997 and guiding the franchise through a Super Bowl victory and numerous playoff appearances. Since his passing, ownership has transitioned to his three daughters.
The current FBI investigation is part of a broader effort to understand what occurred during Irsay’s final months and whether any questions remain about his medical care and treatment choices.

























